Disaccharide structure code for the easy representation of constituent oligosaccharides from glycosaminoglycans

被引：124

作者：

Lawrence, Roger ^{[1
]}

Lu, Hong ^{[2
]}

Rosenberg, Robert D. ^{[3
]}

Esko, Jeffrey D. ^{[1
]}

Zhang, Lijuan ^{[2
]}

机构：

[1] Univ Calif San Diego, Dept Cellular & Mol Med, Glycobiol Res & Training Ctr, La Jolla, CA 92093 USA

[2] Washington Univ, Sch Med, Dept Pathol & Immunol, St Louis, MO 63110 USA

[3] MIT, Dept Biol, Cambridge, MA 02139 USA

来源：

NATURE METHODS | 2008年 / 5卷 / 04期

关键词：

D O I：

10.1038/nmeth0408-291

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Here we introduce a new shorthand nomenclature for designating the disaccharide subunit structure of all glycosaminoglycans as a way to compare compositions and describe linear sequences. Each disaccharide structural code (DSC) comprises four alphanumeric characters that reflect the actual substituents and isomeric characteristics of each component sugar. Larger structures can be represented easily by forming concatamers. The structural transparency of this new nomenclature eliminates the need for ambiguous acronyms or difficult numeric representations.

引用

页码：291 / 292

页数：2

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