Oral endotracheal intubation of rats for intratracheal instillation and aerosol drug delivery

被引：21

作者：

Lizio, R

Westhof, A

Lehr, CM

Klenner, T

机构：

[1] Univ Saarland, Dept Biopharmaceut & Pharmaceut Technol, D-66123 Saarbrucken, Germany

[2] ASTA Medica AG, D-01277 Dresden, Germany

来源：

LABORATORY ANIMALS | 2001年 / 35卷 / 03期

关键词：

endotracheal intubation; rat; large tube; intratracheal aerosol drug administration;

D O I：

10.1258/0023677011911723

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 [兽医学];

摘要：

As reported in the literature, oral endotracheal intubation of rats is considered to be very difficult. Specialised equipment and complicated techniques have been described to perform this procedure. In our experiment we adopted a simple method, which allowed - without any complicated equipment - the insertion of a relatively wide tube into the trachea of rats, allowing drug administration.

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收藏

页码：257 / 260

页数：4

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