Ring-closing metathesis of diolefinic oxazolidinones: a new access to tropanes and aminocyclitols

被引：9

作者：

Agami, C ^{[1
]}

Couty, F ^{[1
]}

Rabasso, N ^{[1
]}

机构：

[1] Univ Paris 06, CNRS, Lab Synth Asmetr, F-75005 Paris, France

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 28期

关键词：

D O I：

10.1016/S0040-4039(01)00830-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Ring-closing metathesis of diolefinic oxazolidinones prepared through N-Boc-2-acyl or alpha,beta -epoxy oxazolidine methodology give stereodefined bicyclic oxazolidinones. The 5,6-membered bicyclic oxazolidinones are then converted into new aminocyclitols by diastereoselective dihydroxylation whereas their 5,7-membered bicyclic homologues are transformed into tropanic alkaloids through an aminocyclization step. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：4633 / 4635

页数：3

共 17 条

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