An indazole synthesis on solid support monitored by single bead FTIR microspectroscopy

被引：35

作者：

Yan, B ^{[1
]}

Gstach, H ^{[1
]}

机构：

[1] SANDOZ FORSCHUNGSINST GES MBH,DEPT IMMUNODERMATOL,VIENNA,AUSTRIA

来源：

TETRAHEDRON LETTERS | 1996年 / 37卷 / 46期

关键词：

D O I：

10.1016/0040-4039(96)01903-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of solid-phase reactions for the synthesis of 1H-indazoles was monitored using Single Bead FTIR Microspectroscopy (single bead IR). The success of the desired reactions has been assessed based on the appearance and disappearance of IR bands characteristic of the starting materials and products for each synthetic step. The results demonstrate again that single bead IR is a valuable technique for monitoring of multi-step solid-phase organic synthesis. Copyright (C) 1996 Elsevier Science Ltd

引用

页码：8325 / 8328

页数：4

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