Eosinophilic esophagitis is a component of the anticonvulsant hypersensitivity syndrome: Description of two cases
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Balatsinou, C.
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G Annunzio Univ & Fdn, Dept Med & Aging Sci, Sect Internal Med & Gastroenterol & Ce SI Fdn, I-66100 Chieti, ItalyG Annunzio Univ & Fdn, Dept Med & Aging Sci, Sect Internal Med & Gastroenterol & Ce SI Fdn, I-66100 Chieti, Italy
Balatsinou, C.
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Milano, A.
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G Annunzio Univ & Fdn, Dept Med & Aging Sci, Sect Internal Med & Gastroenterol & Ce SI Fdn, I-66100 Chieti, ItalyG Annunzio Univ & Fdn, Dept Med & Aging Sci, Sect Internal Med & Gastroenterol & Ce SI Fdn, I-66100 Chieti, Italy
Milano, A.
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Caldarella, M. P.
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G Annunzio Univ & Fdn, Dept Med & Aging Sci, Sect Internal Med & Gastroenterol & Ce SI Fdn, I-66100 Chieti, ItalyG Annunzio Univ & Fdn, Dept Med & Aging Sci, Sect Internal Med & Gastroenterol & Ce SI Fdn, I-66100 Chieti, Italy
Caldarella, M. P.
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Laterza, F.
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G Annunzio Univ & Fdn, Dept Med & Aging Sci, Sect Internal Med & Gastroenterol & Ce SI Fdn, I-66100 Chieti, ItalyG Annunzio Univ & Fdn, Dept Med & Aging Sci, Sect Internal Med & Gastroenterol & Ce SI Fdn, I-66100 Chieti, Italy
Laterza, F.
[1
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Pierdomenico, S. D.
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G Annunzio Univ & Fdn, Dept Med & Aging Sci, Sect Internal Med & Gastroenterol & Ce SI Fdn, I-66100 Chieti, ItalyG Annunzio Univ & Fdn, Dept Med & Aging Sci, Sect Internal Med & Gastroenterol & Ce SI Fdn, I-66100 Chieti, Italy
Pierdomenico, S. D.
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Cuccurullo, F.
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G Annunzio Univ & Fdn, Dept Med & Aging Sci, Sect Internal Med & Gastroenterol & Ce SI Fdn, I-66100 Chieti, ItalyG Annunzio Univ & Fdn, Dept Med & Aging Sci, Sect Internal Med & Gastroenterol & Ce SI Fdn, I-66100 Chieti, Italy
Cuccurullo, F.
[1
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Neri, M.
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G Annunzio Univ & Fdn, Dept Med & Aging Sci, Sect Internal Med & Gastroenterol & Ce SI Fdn, I-66100 Chieti, ItalyG Annunzio Univ & Fdn, Dept Med & Aging Sci, Sect Internal Med & Gastroenterol & Ce SI Fdn, I-66100 Chieti, Italy
Neri, M.
[1
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[1] G Annunzio Univ & Fdn, Dept Med & Aging Sci, Sect Internal Med & Gastroenterol & Ce SI Fdn, I-66100 Chieti, Italy
Anticonvulsant hypersensitivity syndrome is a rare syndrome caused by a specific, severe unusual reaction to antiepileptic agents; anticonvulsant hypersensitivity syndrome develops I week to 3 months after the introduction of the drug and most frequently consists of a multisystemic and multiorgan involvement. Drug withdrawal usually leads to rapid improvement of symptoms. Up to now no oesophageal damage has been described. We present two cases of carbamazepine hypersensitivity syndrome with concomitant development of eosinophilic oesophagitis that resolved after drug withdrawal. (c) 2007 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.