Eosinophilic esophagitis is a component of the anticonvulsant hypersensitivity syndrome: Description of two cases

被引:16
作者
Balatsinou, C. [1 ]
Milano, A. [1 ]
Caldarella, M. P. [1 ]
Laterza, F. [1 ]
Pierdomenico, S. D. [1 ]
Cuccurullo, F. [1 ]
Neri, M. [1 ]
机构
[1] G Annunzio Univ & Fdn, Dept Med & Aging Sci, Sect Internal Med & Gastroenterol & Ce SI Fdn, I-66100 Chieti, Italy
关键词
anticonvulsant hypersensitivity syndrome; carbamazepine; eosinophilic esophagitis;
D O I
10.1016/j.dld.2007.01.017
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Anticonvulsant hypersensitivity syndrome is a rare syndrome caused by a specific, severe unusual reaction to antiepileptic agents; anticonvulsant hypersensitivity syndrome develops I week to 3 months after the introduction of the drug and most frequently consists of a multisystemic and multiorgan involvement. Drug withdrawal usually leads to rapid improvement of symptoms. Up to now no oesophageal damage has been described. We present two cases of carbamazepine hypersensitivity syndrome with concomitant development of eosinophilic oesophagitis that resolved after drug withdrawal. (c) 2007 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.
引用
收藏
页码:145 / 148
页数:4
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