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Design of gene circuits: Lessons from bacteria

被引：173
作者：
Wall, ME
Hlavacek, WS
Savageau, MA
机构：
[1] Los Alamos Natl Lab, Comp & Computat Sci Div, Los Alamos, NM 87545 USA
[2] Los Alamos Natl Lab, Biosci Div, Los Alamos, NM 87545 USA
[3] Los Alamos Natl Lab, Div Theoret, Los Alamos, NM 87545 USA
[4] Univ Calif Davis, Dept Biomed Engn, Davis, CA 95616 USA
来源：
NATURE REVIEWS GENETICS | 2004年 / 5卷 / 01期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1038/nrg1244
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Researchers are now building synthetic circuits for controlling gene expression and considering practical applications for engineered gene circuits. What can we learn from nature about design principles for gene circuits? A large body of experimental data is now available to test some important theoretical predictions about how gene circuits could be organized, but the data also raise some intriguing new questions.
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收藏
页码：34 / 42
页数：9
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