Usefulness of B-type natriuretic peptide as a noninvasive screening tool for cardiac allograft pathology in pediatric heart transplant recipients

被引：36

作者：

Claudius, I

Lan, YT

Chang, RK

Wetzel, GT

Alejos, J

机构：

[1] Childrens Hosp Los Angeles, Div Emergency & Transport Med, Los Angeles, CA 90027 USA

[2] Univ Calif Los Angeles, Harbor Hosp, Dept Pediat, Div Cardiol, Los Angeles, CA USA

[3] Res & Educ Inst, Los Angeles, CA USA

[4] Univ Calif Los Angeles, Mattel Childrens Hosp, Div Pediat Cardiol, Los Angeles, CA USA

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2003年 / 92卷 / 11期

关键词：

D O I：

10.1016/j.amjcard.2003.08.035

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

We examined the utility of B-type natriuretic peptide (BNP) in the evaluation of pediatric orthotopic heart transplant recipients for allograft pathology by measuring the serum BNP levels at the time of either screening echocardiography and biopsy, or at the time of clinical rejection. There was a significant difference (p <0.0001) in the BNP levels in 37 patients in the group with evidence of pathology compared with those without evidence. There was also 100% sensitivity and 100% negative predictive value of BNP levels >100 pg/ml for identifying graft pathology. (C) 2003 by Excerpta Medica, Inc.

引用

页码：1368 / 1370

页数：3

共 19 条

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