Neuroendocrine system of the skin

被引：105

作者：

Slominski, A ^{[1
]}

机构：

[1] Univ Tennessee, Ctr Hlth Sci, Dept Pathol & Lab Med, Memphis, TN 38163 USA

来源：

DERMATOLOGY | 2005年 / 211卷 / 03期

关键词：

neuroendocrine system; cutaneous; neuropeptides; hormones; neurohormones; steroids; secosteroids; hypothalamic-pituitary-adrenal axis; serotoninergic/melatoninergic system; hypothalamic-pituitary-thyroid axis;

D O I：

10.1159/000087012

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Evidence is accumulating that the skin can serve as a peripheral neuroendocrine organ. The skin neuroendocrine activities are predominantly independent of regulation from the central level ( which controls classical hormone secretion) but are rather regulated by local cutaneous factors. These endocrine factors would represent an exquisite regulatory layer addressed at restricting maximally the effect of noxious agents in the skin to preserve local and consequently global homeostasis.

引用

页码：199 / 208

页数：10

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