The proposed terminology 'A1c-derived average glucose' is inherently imprecise and should not be adopted

被引:37
作者
Bloomgarden, Z. T. [1 ]
Inzucchi, S. E. [2 ]
Karnieli, E. [3 ]
Le Roith, D. [1 ]
机构
[1] Mt Sinai Sch Med, New York, NY 10028 USA
[2] Yale Univ, Sch Med, New Haven, CT USA
[3] Rambam Med Ctr, Haifa, Israel
关键词
glycated haemoglobin;
D O I
10.1007/s00125-008-1027-7
中图分类号
R5 [内科学];
学科分类号
1002 [临床医学]; 100201 [内科学];
摘要
The proposed use of a more precise standard for glycated (A(1c)) and non-glycated haemoglobin would lead to an A(1c) value, when expressed as a percentage, that is lower than that currently in use. One approach advocated to address the potential confusion that would ensue is to replace 'HbA(1c)' with a new term, 'A(1c)-derived average glucose.' We review evidence from several sources suggesting that A(1c) is, in fact, inherently imprecise as a measure of average glucose, so that the proposed terminology should not be adopted.
引用
收藏
页码:1111 / 1114
页数:4
相关论文
共 31 条
[1]
Type 1 diabetes and glucose monitoring [J].
Bloomgarden, Zachary T. .
DIABETES CARE, 2007, 30 (11) :2965-2971
[2]
Conditions associated with very low values of glycohaemoglobin measured by an HPLC method [J].
Camargo, JL ;
Gross, JL .
JOURNAL OF CLINICAL PATHOLOGY, 2004, 57 (04) :346-349
[3]
CHALEW S, 2008, DIABETES, V56, P1913
[4]
Chalew Stuart, 2008, Diabetes, V57, pe5, DOI 10.2337/db07-1569
[5]
Is poor, glycemic control associated with reduced red blood cell lifespan? [J].
Cohen, RM ;
Franco, R ;
Joiner, CH .
DIABETES CARE, 2004, 27 (04) :1013-1014
[6]
Discordance between HbA1c and fructosamine -: Evidence for a glycosylation gap and its relation to diabetic nephropathy [J].
Cohen, RM ;
Holmes, YR ;
Chenier, TC ;
Joiner, CH .
DIABETES CARE, 2003, 26 (01) :163-167
[7]
Relationship of prospective GHb to glycated serum proteins in incident diabetic retinopathy - Implications of the glycation gap for mechanism of risk prediction [J].
Cohen, Robert M. ;
LeCaire, Tamara J. ;
Lindsell, Christopher J. ;
Smith, Eric P. ;
D'Alessio, Donn J. .
DIABETES CARE, 2008, 31 (01) :151-153
[8]
A1C: Does one size fit all? [J].
Cohen, Robert M. .
DIABETES CARE, 2007, 30 (10) :2756-2758
[9]
Evidence for independent heritability of the glycation gap, (glycosylation gap) fraction of HbA1c in nondiabetic twins [J].
Cohen, Robert M. ;
Snieder, Harold ;
Lindsell, Christopher J. ;
Beyan, Huriya ;
Hawa, Mohammed I. ;
Blinko, Stuart ;
Edwards, Raymond ;
Spector, Timothy D. ;
Leslie, R. David G. .
DIABETES CARE, 2006, 29 (08) :1739-1743
[10]
How should HbA1c measurements be reported? [J].
Gorus, F ;
Mathieu, C ;
Gerlo, E .
DIABETOLOGIA, 2006, 49 (01) :7-10