Geranins C and D, additional new antiprotozoal A-type proanthocyanidins from Geranium niveum

被引：33

作者：

Calzada, F

Cedillo-Rivera, R

Bye, R

Mata, R ^{[1
]}

机构：

[1] Univ Nacl Autonoma Mexico, Fac Quim, Mexico City 04510, DF, Mexico

[2] Univ Nacl Autonoma Mexico, Inst Biol, Jardin Bot, Mexico City 04510, DF, Mexico

[3] Hosp Pediat Mexico City, Ctr Med Nacl Sigjlo XXI, IMSS, Unidad Invest Med Enfermedades Infecciosas & Para, Mexico City 04510, DF, Mexico

[4] Hosp Pediat Mexico City, Ctr Med Nacl Sigjlo XXI, IMSS, Unidad Invest Med Farmacol Prod Nat, Mexico City 04510, DF, Mexico

来源：

PLANTA MEDICA | 2001年 / 67卷 / 07期

关键词：

D O I：

10.1055/s-2001-17358

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Two new additional A-type proanthocyanidins have been isolated from Geranium niveum. Their structures were determined by spectroscopic, chemical and chiroptical methods as epi-afzelechin-(4 beta -->8,2 beta -->O -->7)-gallocatechin (1) and epi-afzelechin-(4 beta -->8,2 beta -->O -->7)-afzelechin-(4 beta -->8,2 beta -->O -->7)-afzelechin (2). Proanthocyanidins 1 and 2 were given the trivial names of geranins C and D, respectively. Compound 2 showed moderate antiprotozoal activity against Entamoeba histolytica and Giardia lamblia, whereas 1 exhibited weak activity toward E. histolytica.

引用

页码：677 / 680

页数：4

共 5 条

[1] OLIGOMERIC PROANTHOCYANIDINS POSSESSING A DOUBLY LINKED STRUCTURE FROM PAVETTA-OWARIENSIS [J].