Prognostic significance and measurement of exercise-derived hemodynamic variables in patients with heart failure

被引:64
作者
Lang, Chim C. [1 ,2 ]
Agostoni, Piergiuseppe [3 ]
Mancini, Donna M. [1 ]
机构
[1] Columbia Presbyterian Med Ctr, Div Cardiol, New York, NY 10032 USA
[2] Univ Dundee, Ninewells Hosp & Med Sch, Div Med & Therapeut, Dundee DD1 9SY, Scotland
[3] Univ Milan, Ctr Cardiol Monzino, IRCCS, Ist Cardiol, Milan, Italy
关键词
chronic heart failure; cardiac transplantation; exercise; cardiac output;
D O I
10.1016/j.cardfail.2007.05.004
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The peak VO2 is an important prognostic measurement in the evaluation of patients with heart failure and is used to monitor the progress of the condition, especially in selecting patients for cardiac transplantation. However, peak VO2 may be influenced by noncardiac factors such as age, sex, motivation, anemia, and muscle deconditioning. These confounding factors may diminish somewhat the prognostic power of peak VO2 Several groups have looked at exercise-derived variables beyond peak VO2 to assess whether a more direct assessment of cardiac function, using exercise-derived hemodynamic variables, may yield more precise prognostic information than standard cardiopulmonary-derived data. This article reviews the evidence that cardiac work related to exercise may enhance the prognostic value of peak VO2 in the evaluation of patients with heart failure and briefly discusses the available methods for measuring these parameters.
引用
收藏
页码:672 / 679
页数:8
相关论文
共 55 条
[1]  
AARONSON KD, 1995, J HEART LUNG TRANSPL, V14, P981
[2]   Development and prospective validation of a clinical index to predict survival in ambulatory patients referred for cardiac transplant evaluation [J].
Aaronson, KD ;
Schwartz, JS ;
Chen, TM ;
Wong, KL ;
Goin, JE ;
Mancini, DM .
CIRCULATION, 1997, 95 (12) :2660-2667
[3]   Noninvasive measurement of cardiac output during exercise by inert gas rebreathing technique: A new tool for heart failure evaluation [J].
Agostoni, P ;
Cattadori, G ;
Apostolo, A ;
Contini, M ;
Palermo, P ;
Marenzi, G ;
Wasserman, K .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2005, 46 (09) :1779-1781
[4]   Non-invasive measurement of stroke volume during exercise in heart failure patients [J].
Agostoni, PG ;
Wasserman, K ;
Perego, GB ;
Guazzi, M ;
Cattadori, G ;
Palermo, P ;
Lauri, G ;
Marenzi, G .
CLINICAL SCIENCE, 2000, 98 (05) :545-551
[5]   Development of a ventilatory classification system in patients with heart failure [J].
Arena, Ross ;
Myers, Jonathan ;
Abella, Joshua ;
Peberdy, Mary Ann ;
Bensimhon, Daniel ;
Chase, Paul ;
Guazzi, Marco .
CIRCULATION, 2007, 115 (18) :2410-2417
[6]   INFLUENCE OF AGE AND SEX ON EXERCISE CARDIAC OUTPUT [J].
BECKLAKE, MR ;
FRANK, H ;
DAGENAIS, GR ;
OSTIGUY, GL ;
GUZMAN, CA .
JOURNAL OF APPLIED PHYSIOLOGY, 1965, 20 (05) :938-&
[7]   Comparison of impedance cardiography with thermodilution and direct fick methods for noninvasive measurement of stroke volume and cardiac output during incremental exercise in patients with ischemic cardiomyopathy [J].
Belardinelli, R ;
Ciampani, N ;
Costantini, C ;
Blandini, A ;
Purcaro, A .
AMERICAN JOURNAL OF CARDIOLOGY, 1996, 77 (15) :1293-1301
[8]  
Bennett L E, 2001, Clin Transpl, P25
[9]  
Butler J, 2004, CIRCULATION, V110, P605
[10]   Hemodynamic exercise testing - A valuable tool in the selection of cardiac transplantation candidates [J].
Chomsky, DB ;
Lang, CC ;
Rayos, GH ;
Shyr, Y ;
Yeoh, TK ;
Pierson, RN ;
Davis, SF ;
Wilson, JR .
CIRCULATION, 1996, 94 (12) :3176-3183