Differentiating solitary pulmonary metastases in patients with renal cell carcinomas by 18F-fluoro-2-deoxyglucose positron emission tomography -: A preliminary report

被引:15
作者
Chang, CH
Shiau, YC
Shen, YY
Kao, A
Lin, CC
Lee, CC
机构
[1] China Med Coll Hosp, Dept Nucl Med, Taichung 404, Taiwan
[2] China Med Coll Hosp, Dept Med Res, Taichung 404, Taiwan
[3] China Med Coll Hosp, Dept Urol, Taichung 404, Taiwan
[4] China Med Coll Hosp, Dept Nucl Med, Taichung 404, Taiwan
[5] China Med Coll Hosp, Dept Family Med, Taichung 404, Taiwan
[6] Natl Taiwan Univ, Coll Elect Engn, Far Eastern Mem Hosp, Dept Nucl Med, Taipei, Taiwan
[7] Natl Taiwan Univ, Coll Elect Engn, Inst Biomed Engn, Taipei, Taiwan
[8] Shin Kong Wu Ho Su Mem Hosp, Dept Nucl Med, Taipei, Taiwan
[9] Shin Kong Wu Ho Su Mem Hosp, PET Ctr, Taipei, Taiwan
关键词
F-18-fluoro-2-deoxyglucose; positron emission; tomography; solitary pulmonary metastases; renal cell carcinoma;
D O I
10.1159/000072683
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 [临床医学]; 100201 [内科学];
摘要
Objective: This preliminary study was to evaluate the characteristics of indeterminate solitary pulmonary lesions in patients with renal cell carcinomas (RCC) using F-18-fluoro-2-deoxyglucose positron emission tomography (FDG-PET). Material and Methods: Fifteen patients with RCC were found to have solitary pulmonary lesions with indeterminate chest X-ray and CT findings. Pulmonary metastases were suspected in all cases so whole body surveys with FDG-PET were performed. Results: FDG-PET correctly identified 9 true-positive and 4 true-negative cases. However, FDG-PET failed to interpret 1 false-positive and 1 false-negative case. Standard uptake values (SUV) were used as parameters to differentiate the solitary pulmonary lesions. Using SUV >2.5 as the cutoff to diagnose malignancy, the sensitivity, specificity, and accuracy of FDG-PET were 90, 80, and 87%, respectively. Conclusion: We conclude that FDG-PET is an accurate modality to differentiate solitary pulmonary lesions in patients with RCC. Copyright (C) 2003 S. Karger AG, Basel.
引用
收藏
页码:306 / 309
页数:4
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