Phage-displayed peptide libraries

被引：103

作者：

Zwick, MB

Shen, JQ

Scott, J

机构：

[1] Simon Fraser Univ, Inst Mol Biol & Biochem, Biochem Program, Burnaby, BC V5A 1S6, Canada

[2] Simon Fraser Univ, Inst Mol Biol & Biochem, Dept Biol Sci, Burnaby, BC V5A 1S6, Canada

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 1998年 / 9卷 / 04期

关键词：

D O I：

10.1016/S0958-1669(98)80017-7

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Over the past year, significant advances have been achieved through the use of phage-displayed peptide libraries. A wide variety of bioactive molecules, including antibodies, receptors and enzymes, have selected high-affinity and/or highly-specific peptide ligands from a number of different types of peptide library. The demonstrated therapeutic potential of some of these peptides, as well as new insights into protein structure and function that peptide ligands have provided, highlight the progress made within this rapidly-expanding field.

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收藏

页码：427 / 436

页数：10

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