Delayed Treatment of Delirium Increases Mortality Rate in Intensive Care Unit Patients

被引：103

作者：

Heymann, A. ^{[2
]}

Radtke, F. ^{[2
]}

Schiemann, A. ^{[2
]}

Luetz, A. ^{[2
]}

MacGuill, M. ^{[2
]}

Wernecke, K. D. ^{[1
,2
]}

Spies, C. ^{[2
]}

机构：

[1] SOSTANA GmbH, Berlin, Germany

[2] Charite, Dept Anaesthesiol & Intens Care Med, D-13353 Berlin, Germany

来源：

JOURNAL OF INTERNATIONAL MEDICAL RESEARCH | 2010年 / 38卷 / 05期

关键词：

THERAPY; DELIRIUM; INTENSIVE CARE UNIT; THERAPY DELAY; OUTCOME; ALCOHOL-WITHDRAWAL; SEVERITY; RELIABILITY; VALIDITY; THERAPY; IMPACT; SCORE; ICU;

D O I：

10.1177/147323001003800503

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

100103 [病原生物学]; 100218 [急诊医学];

摘要：

Delirium in the intensive care unit (ICU) is a serious complication associated with a poor outcome in critically ill patients. In this prospective observational study of the effect of a delay in delirium therapy on mortality rate, 418 ICU patients were regularly assessed using the Delirium Detection Score (DDS). The departmental standard required that if delirium was diagnosed (DDS > 7), therapy should be started within 24 h. In total, 204 patients (48.8%) were delirious during their ICU stay. In 184 of the delirious patients (90.2%), therapy was started within 24 h; in 20 patients (9.8%), therapy was delayed. During their ICU stay, patients whose delirium treatment was delayed were more frequently mechanically ventilated, had more nosocomial infections (including pneumonia) and had a higher mortality rate than patients whose treatment was not delayed. Thus, it would appear that a delay in initiating delirium therapy in ICU patients was associated with increased mortality.

引用

页码：1584 / 1595

页数：12

共 29 条

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