Straightforward access to methyl-polyheterocycles from direct para-lithiation of 3-picoline

被引：23

作者：

Mathieu, J ^{[1
]}

Gros, P ^{[1
]}

Fort, Y ^{[1
]}

机构：

[1] Univ Nancy 1, UMR CNRS UHP 7565, Fac Sci Synth Organ & React, F-54506 Vandoeuvre Les Nancy, France

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 10期

关键词：

D O I：

10.1016/S0040-4039(01)00033-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Various heterocycles have been introduced on the 3-picoline nucleus via a regioselective BuLi-Me2N(CH2)(2)OLi (BuLi-LiDMAE) mediated para-lithiation. Useful methyl-polyheterocycles were efficiently prepared by a one-pot lithiation-stannylation-Stille coupling sequence. (C) 2001 Published by Elsevier Science Ltd.

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页码：1879 / 1881

页数：3

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