Antibodies to Clp protease in primary biliary cirrhosis: possible role of a mimicking T-cell epitope

被引:27
作者
Baum, H
Bogdanos, DP
Vergani, D
机构
[1] Kings Coll London, Div Life Sci, London WC1E 6HX, England
[2] UCL, Sch Med, Inst Hepatol, Immunol Grp, London WC1E 6HX, England
关键词
D O I
10.1016/S0168-8278(01)00059-9
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
引用
收藏
页码:785 / 787
页数:3
相关论文
共 9 条
[1]   Biochemistry and autoimmune response to the 2-oxoacid dehydrogenase complexes in primary biliary cirrhosis [J].
Bassendine, MF ;
Jones, DEJ ;
Yeaman, SJ .
SEMINARS IN LIVER DISEASE, 1997, 17 (01) :49-60
[2]   Double reactivity to Ecoli/Pyruvate Dehydrogenase Complex-E2 characterises primary biliary cirrhosis [J].
Bogdanos, DP ;
Grasso, A ;
Okamoto, M ;
Butler, P ;
Williams, R ;
Baum, H ;
Burroughs, AK ;
Vergani, D .
JOURNAL OF HEPATOLOGY, 2000, 32 :39-39
[3]   MOLECULAR MIMICRY IN LIVER-DISEASE [J].
BURROUGHS, AK ;
BUTLER, P ;
STERNBERG, MJE ;
BAUM, H .
NATURE, 1992, 358 (6385) :377-378
[4]   Primary biliary cirrhosis: an orchestrated immune response against epithelial cells [J].
Gershwin, ME ;
Ansari, AA ;
Mackay, IR ;
Nakanuma, Y ;
Nishio, A ;
Rowley, MJ ;
Coppel, RL .
IMMUNOLOGICAL REVIEWS, 2000, 174 :210-225
[5]   PBC: an infectious disease? [J].
Haydon, GH ;
Neuberger, J .
GUT, 2000, 47 (04) :586-588
[6]  
Joplin R, 2000, FALK SYMP, V114, P268
[7]   Molecular mimicry and the role of B lymphocytes in the processing of autoantigens [J].
Liang, B ;
Mamula, MJ .
CELLULAR AND MOLECULAR LIFE SCIENCES, 2000, 57 (04) :561-568
[8]   Antibodies against the COOH-terminal region of E-coli ClpP protease in patients with primary biliary cirrhosis [J].
Mayo, I ;
Arizti, P ;
Parés, A ;
Oliva, J ;
Doforno, RA ;
de Sagarra, MR ;
Rodés, J ;
Castaño, JG .
JOURNAL OF HEPATOLOGY, 2000, 33 (04) :528-536
[9]   The structure of ClpP at 2.3 angstrom resolution suggests a model for ATP-dependent proteolysis [J].
Wang, JM ;
Hartling, JA ;
Flanagan, JM .
CELL, 1997, 91 (04) :447-456