Kinin receptors

被引：127

作者：

Marceau, F ^{[1
]}

Bachvarov, DR ^{[1
]}

机构：

[1] CHU Quebec, Ctr Rech, Quebec City, PQ G1R 2J6, Canada

来源：

CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY | 1998年 / 16卷 / 04期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1007/BF02737658

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Rapid developments are expected in the molecular pharmacology of both B1, and B2 types of kinin receptors, since the underlying genetic structures are now known and widely studied. The consequences of kinin receptor duality and physiopathological regulation have not yet been fully appreciated. Medicinal chemistry is also an active front of research in kinin pharmacology, as more effective drugs targeted at kinin receptors are regularly reported. Various complementary molecular approaches (the receptor binding, cloning, immunoreacting, mutagenesis, inactivation, the study of regulation, allelic polymorphisms, and so forth) are expanding our knowledge of the role of kinins in allergy, inflammation, and singularly, renal medicine.

引用

页码：385 / 401

页数：17

共 95 条

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