Diabetic ketoacidosis in pregnancy tends to occur at lower blood glucose levels: Case-control study and a case report of euglycemic diabetic ketoacidosis in pregnancy

被引:64
作者
Guo, Rui-Xia [1 ]
Yang, Ling-Zhu [1 ]
Li, Liu-Xia [1 ]
Zhao, Xue-Ping [1 ]
机构
[1] Zheng Zhou Univ, Affiliated Hosp 1, Dept Obstet & Gynecol, Zhengzhou 450052, Peoples R China
关键词
diabetes mellitus; medical problems in pregnancy; obstetric complication; stillbirth;
D O I
10.1111/j.1447-0756.2008.00720.x
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Background and Objective: The occurrence of diabetic ketoacidosis (DKA) during pregnancy is considered a medical emergency. The aims of the present study were to evaluate the incidence of DKA in pregnant and non-pregnant women with diabetes; to compare the blood glucose levels at the diagnosis of DKA in pregnant and non-pregnant women; and to show a case of euglycemic DKA in pregnancy. Methods: The subjects consisted of 90 cases of DKA in pregnant women with diabetes and 286 cases of non-pregnant female inpatients receiving treatment for diabetes during 2001 to 2005 in our hospital. The incidence of DKA in pregnant and non-pregnant women with diabetes and the blood glucose levels at the diagnosis of DKA in pregnant and non-pregnant women were compared. Results: DKA had a higher incidence in pregnant women with diabetes (8/90, 8.9%) than in non-pregnant women with diabetes (9/286, 3.1%) (P < 0.05). The blood glucose levels (mmol/L) in pregnant women with DKA were significantly lower than those in non-pregnant women with DKA (16.3 +/- 4.6 vs 27.5 +/- 4.8, P < 0.001). A case of euglycemic DKA in pregnancy was described whose serum glucose level was only 6.9 mmol/L. Conclusions: DKA in pregnant women with diabetes may occur more frequently, and at lower blood glucose levels than DKA in non-pregnant women with diabetes.
引用
收藏
页码:324 / 330
页数:7
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