Lessons from eQTL mapping studies: non-coding regions and their role behind natural phenotypic variation in plants

被引：65

作者：

Cubillos, Francisco A. ^{[1
]}

Coustham, Vincent ^{[1
]}

Loudet, Olivier ^{[1
]}

机构：

[1] Inst Jean Pierre Bourgin, INRA AgroParisTech UMR1318, F-78000 Versailles, France

来源：

CURRENT OPINION IN PLANT BIOLOGY | 2012年 / 15卷 / 02期

关键词：

GENE-EXPRESSION; REGULATORY VARIATION; ARABIDOPSIS; ARCHITECTURE; COMPLEX; IDENTIFICATION; RESISTANCE; EVOLUTION; NETWORKS; TRAITS;

D O I：

10.1016/j.pbi.2012.01.005

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Even if considerable progress has been achieved towards the understanding of natural variation in plant systems, the contribution of transcript abundance variation to phenotypic diversity remains unappreciated. Over the last decade, efforts to characterise the genome-wide expression variation in natural accessions, structured populations and hybrids have improved our knowledge of the contribution of non-coding polymorphisms to gene expression regulation. Moreover, new studies are helping to unravel the role of expression polymorphisms and their orchestrated performance. Recent advances involving classical linkage analysis, GWAS and improved eQTL mapping strategies will provide a greater resolution to determine the genetic variants shaping the broad diversity in plant systems.

引用

页码：192 / 198

页数：7

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