Chitosan derivatives as chiral selectors bonded on allyl silica gel:: preparation, characterisation and study of the resulting high-performance liquid chromatography chiral stationary phases

被引：59

作者：

Senso, A

Oliveros, L

Minguillón, C

机构：

[1] Univ Barcelona, Fac Farm, Quim Farmaceut Lab, E-08028 Barcelona, Spain

[2] Conservatoire Natl Arts & Metiers, Lab Chim Gen, F-75141 Paris 03, France

来源：

JOURNAL OF CHROMATOGRAPHY A | 1999年 / 839卷 / 1-2期

关键词：

chiral stationary phases; LC; enantiomer separation; chitosan;

D O I：

10.1016/S0021-9673(99)00072-2

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Several mixed 10-undecenoyl/phenylaminocarbonyl or benzoyl derivatives of chitosan, differently substituted in the aromatic ring, were prepared, characterized and immobilized on allylsilica gel. The resulting high-performance liquid chromatography (HPLC) chiral supports were tested chromatographically. The influence of the starting polysaccharidic material, as well as that of the solvents used as mobile phase modifiers, on the preparation and performance of the resulting chiral stationary phases (CSPs) is discussed. (C) 1999 Elsevier Science B.V. All rights reserved.

引用

页码：15 / 21

页数：7

共 12 条

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Cass QB, 1996, CHIRALITY, V8, P131

[2] 3,5-dimethylphenylcarbamates of amylose, chitosan and cellulose bonded on silica gel - Comparison of their chiral recognition abilities as high-performance liquid chromatography chiral stationary phases [J].