Diagnosis of periarticular osteoporosis in rheumatoid arthritis using digital X-ray radiogrammetry

被引：24

作者：

Boettcher, Joachim ^{[1
]}

Pfeil, Alexander ^{[1
]}

机构：

[1] Univ Jena, Inst Diag & Intervent Radiol, D-07747 Jena, Germany

来源：

ARTHRITIS RESEARCH & THERAPY | 2008年 / 10卷 / 01期

关键词：

D O I：

10.1186/ar2352

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Osteoporosis can manifest in two ways in rheumatoid arthritis: generalized bone loss, which may result from immobility, the inflammatory process per se and/or treatments such as steroids; and periarticular demineralization, which is probably due to local release of inflammatory agents. Digital X-ray radiogrammetry (DXR) is an effective and sensitive modality for monitoring periarticular osteoporosis, which is among the earliest features of rheumatoid arthritis, preceding bone erosions. DXR is a promising technique, which can provide quantitative data that allow early diagnosis. During the course of rheumatoid arthritis it can be deployed in combination with established X-ray scoring methods to inform decisions regarding the optimal therapy to prevent joint destruction.

引用

页数：3

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