In vitro activities of doripenem and comparator agents against 364 anaerobic clinical isolates

被引：38

作者：

Wexler, HM

Engel, AE

Glass, D

Li, CD

机构：

[1] Greater Los Angeles Vet Adm Hlth Care Serv, Med & Res Serv, Los Angeles, CA USA

[2] Univ Calif Los Angeles, Sch Med, Dept Med, Los Angeles, CA 90024 USA

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2005年 / 49卷 / 10期

关键词：

D O I：

10.1128/AAC.49.10.4413-4417.2005

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The in vitro activities of doripenem against 364 anaerobic isolates were measured and compared to those of ertapenem, imipenem, meropenem, ceftriaxone, and levotloxacin. All of the carbapenems were active against nearly all Bacteroides fragilis group isolates. Doripenem was either comparable to or slightly less active than imipenem and meropenem against most isolates but more active than the other penems against Clostridium difficile. Doripenem appears to have excellent activity against a broad range of anaerobes.

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收藏

页码：4413 / 4417

页数：5

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