How does radiation kill cells?

被引：257

作者：

Cohen-Jonathan, E ^{[1
]}

Bernhard, EJ ^{[1
]}

McKenna, WG ^{[1
]}

机构：

[1] Univ Penn, Dept Radiat Oncol, Philadelphia, PA 19104 USA

来源：

CURRENT OPINION IN CHEMICAL BIOLOGY | 1999年 / 3卷 / 01期

关键词：

D O I：

10.1016/S1367-5931(99)80014-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

Recent advances in the understanding of intracellular signaling after genotoxic injury have led to a better understanding of the pathways that influence radiation-induced cell death. Particular progress has been made in defining molecular controls of apoptosis and radiation-induced cell cycle arrest, as well as the possible role of telomerase activity in stabilizing DNA breaks.

引用

页码：77 / 83

页数：7

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