Neuroscience - Microglia: The enemy within?

被引：114

作者：

Kempermann, G ^{[1
]}

Neumann, H

机构：

[1] Max Delbruck Ctr Mol Med, Neuronal Stem Cells Res Grp, D-13125 Berlin, Germany

[2] European Neurosci Inst Gottingen, Neuroimmunol Unit, D-37073 Gottingen, Germany

来源：

SCIENCE | 2003年 / 302卷 / 5651期

关键词：

D O I：

10.1126/science.1092864

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

[No abstract available]

引用

页码：1689 / 1690

页数：2

共 7 条

[1] CXCR4-activated astrocyte glutamate release via TNFa: amplification by microglia triggers neurotoxicity [J].

Bezzi, P ;

Domercq, M ;

Brambilla, L ;

Galli, R ;

Schols, D ;

De Clercq, E ;

Vescovi, A ;

Bagetta, G ;

Kollias, G ;

Meldolesi, J ;

Volterra, A .

NATURE NEUROSCIENCE, 2001, 4 (07) :702-710

[2] Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathway [J].

Bonni, A ;

Sun, Y ;

NadalVicens, M ;

Bhatt, A ;

Frank, DA ;

Rozovsky, I ;

Stahl, N ;

Yancopoulos, GD ;

Greenberg, ME .

SCIENCE, 1997, 278 (5337) :477-483

[3] Inflammation is detrimental for neurogenesis in adult brain [J].

Ekdahl, CT ;

Claasen, JH ;

Bonde, S ;

Kokaia, Z ;

Lindvall, O .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2003, 100 (23) :13632-13637

[4] CYTOKINE REGULATION OF NEURONAL DIFFERENTIATION OF HIPPOCAMPAL PROGENITOR CELLS [J].

MEHLER, MF ;

ROZENTAL, R ;

DOUGHERTY, M ;

SPRAY, DC ;

KESSLER, JA .

NATURE, 1993, 362 (6415) :62-65

[5] Inflammatory blockade restores adult hippocampal neurogenesis [J].

Monje, ML ;

Toda, H ;

Palmer, TD .

SCIENCE, 2003, 302 (5651) :1760-1765

[6] Irradiation induces neural precursor-cell dysfunction [J].

Monje, ML ;

Mizumatsu, S ;

Fike, JR ;

Palmer, TD .

NATURE MEDICINE, 2002, 8 (09) :955-962

[7] Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants [J].

Santarelli, L ;

Saxe, M ;

Gross, C ;

Surget, A ;

Battaglia, F ;

Dulawa, S ;

Weisstaub, N ;

Lee, J ;

Duman, R ;

Arancio, O ;

Belzung, C ;

Hen, R .

SCIENCE, 2003, 301 (5634) :805-809

← 1 →