Bispectral analysis of complex patterns of sympathetic nerve discharge

被引:13
作者
Gebber, GL [2 ]
Zhong, S
Paitel, Y
机构
[1] MICHIGAN STATE UNIV, DEPT PHYSIOL, E LANSING, MI 48824 USA
[2] MICHIGAN STATE UNIV, DEPT PHARMACOL TOXICOL, E LANSING, MI 48824 USA
关键词
bicoherence; cardiac-related and 10-Hz rhythms; frequency locking; irregular 2- to 6-Hz oscillations; low-frequency noncardiac-related rhythm; nonlinear phase locking; quasiperiodicity;
D O I
10.1152/ajpregu.1996.271.5.R1173
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
Bispectral analysis was used to demonstrate quadratic nonlinear coupling (i.e., phase locking) of different frequency components in inferior cardiac sympathetic nerve discharge (SND) of urethan-anesthetized cats. The complex patterns of SND analyzed included mixtures of 1) the cardiac-related and 10-Hz rhythms, 2) the 10-Hz rhythm and irregular 2- to 6-Hz oscillations, and 3) the 10-Hz rhythm and a lower frequency non-cardiac-related rhythm near 4 Hz. In some cases, the bicoherence function (normalized bispectrum) showed no phase locking of these frequency components. Cases of nil bicoherence are equated with linear superposition of frequency components, which implies the existence of multiple and noninteractive central circuits. Increased complexity of SND was observed in other cases, as evidenced by significant phase locking of different frequency components with or without frequency locking. Frequency locking (higher frequency rhythm is a multiple of lower) was confirmed by constructing Lissajous orbital plots showing covariation of voltages in selectively filtered bands of SND. We equate frequency locking with nonlinear coupling of the central generators of different sympathetic nerve rhythms and phase locking without frequency locking possibly with nonlinearities arising at levels below noncoupled central rhythm generators.
引用
收藏
页码:R1173 / R1185
页数:13
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