A thorny question: how does activity maintain dendritic spines?

被引：33

作者：

Andersen, P ^{[1
]}

Soleng, AF ^{[1
]}

机构：

[1] Univ Oslo, Inst Basic Med Sci, Dept Neurophysiol, N-0317 Oslo, Norway

来源：

NATURE NEUROSCIENCE | 1999年 / 2卷 / 01期

关键词：

D O I：

10.1038/4506

中图分类号：

Q189 [神经科学];

学科分类号：

071006 [神经生物学];

摘要：

Most central excitatory synapses occur on dendritic spines. A new study shows that spine stability depends on spontaneous glutamate release and AMPA receptors.

引用

页码：5 / 7

页数：3

共 15 条

[1]

ANDERSEN P, 1966, EXP BRAIN RES, V1, P236

[2]

Dendritic spine density and LTP induction in cultured hippocampal slices [J].

Collin, C ;

Miyaguchi, K ;

Segal, M .

JOURNAL OF NEUROPHYSIOLOGY, 1997, 77 (03) :1614-1623

[3]

Rapid actin-based plasticity in dendritic spines [J].

Fischer, M ;

Kaech, S ;

Knutti, D ;

Matus, A .

NEURON, 1998, 20 (05) :847-854

[4]

GRAY EG, 1959, J ANAT, V93, P420

[5]

ELECTRON-MICROSCOPIC STUDY OF LESION-INDUCED SYNAPTOGENESIS IN DENTATE GYRUS OF ADULT RAT .1. MAGNITUDE AND TIME COURSE OF DEGENERATION [J].

MATTHEWS, DA ;

COTMAN, C ;

LYNCH, G .

BRAIN RESEARCH, 1976, 115 (01) :1-21

[6]

HIGH ACTIN CONCENTRATIONS IN BRAIN DENDRITIC SPINES AND POSTSYNAPTIC DENSITIES [J].

MATUS, A ;

ACKERMANN, M ;

PEHLING, G ;

BYERS, HR ;

FUJIWARA, K .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1982, 79 (23) :7590-7594

[7]

INSITU LOCALIZATION OF MYOSIN AND ACTIN IN DENDRITIC SPINES WITH THE IMMUNOGOLD TECHNIQUE [J].

MORALES, M ;

FIFKOVA, E .

JOURNAL OF COMPARATIVE NEUROLOGY, 1989, 279 (04) :666-674

[8]

AN INCREASE IN DENDRITIC SPINE DENSITY ON HIPPOCAMPAL CA1 PYRAMIDAL CELLS FOLLOWING SPATIAL-LEARNING IN ADULT-RATS SUGGESTS THE FORMATION OF NEW SYNAPSES [J].

MOSER, MB ;

TROMMALD, M ;

ANDERSEN, P .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (26) :12673-12675

[9]

Morphological plasticity of dendritic spines in central neurons is mediated by activation of cAMP response element binding protein [J].

Murphy, DD ;

Segal, M .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (04) :1482-1487

[10]

Ramon y Cajal S, 1989, RECOLLECTIONS MY LIF

← 1 2 →