Borna disease virus RNA in peripheral blood mononuclear cells obtained from healthy dairy cattle

被引：33

作者：

Hagiwara, K

Nakaya, T

Nakamura, Y

Asahi, S

Takahashi, H

Ishihara, C

Ikuta, K

机构：

[1] HOKKAIDO UNIV,INST IMMUNOL SCI,SECT SEROL,KITA KU,SAPPORO,HOKKAIDO 060,JAPAN

[2] RAKUNO GAKUEN UNIV,SCH VET MED,DEPT ANIM MODEL,EBETSU,HOKKAIDO 069,JAPAN

来源：

MEDICAL MICROBIOLOGY AND IMMUNOLOGY | 1996年 / 185卷 / 03期

关键词：

Borna disease virus; cattle; peripheral blood mononuclear cells; reverse transcriptase-polymerase chain reaction;

D O I：

10.1007/s004300050024

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We examined natural infection of Borna disease virus (BDV) in 74 healthy dairy cattle in Japan. The seroprevalence determined using recombinant BDV p24 protein was 20.3%. The prevalence of BDV RNA in peripheral blood mononuclear cells (PBMCs) determined by polymerase chain reaction for p24 was 10.8%. Cell fraction of the PBMCs revealed the presence of BDV RNA in the T cell-enriched fraction. Thus, BDV infection is wide-spread even among healthy cattle.

引用

页码：145 / 151

页数：7

共 33 条

[1]

BAHMANI MK, 1996, IN PRESS VIRUS RES

[2] A NOVEL MARKER FOR BORNA-DISEASE VIRUS-INFECTION [J].