Treatment of pneumococcal meningitis with dexamethasone

被引：1

作者：

Felipe Rucian, A. ^{[2
]}

Garcia Del Cerro, G. ^{[2
]}

Coll Usandizaga, F. ^{[2
]}

Tobena Rue, M. ^{[2
]}

Martinez Gomez, X. ^{[3
]}

Moraga-Llop, F. A. ^{[1
]}

机构：

[1] Univ Autonoma Barcelona, Hosp Univ Vall Hebron, Unidad Patol Infecciosa & Inmunodeficiencias Pedi, E-08193 Barcelona, Spain

[2] Univ Autonoma Barcelona, Hosp Univ Vall Hebron, Serv Pediat, E-08193 Barcelona, Spain

[3] Univ Autonoma Barcelona, Hosp Univ Vall Hebron, Serv Med Prevent, E-08193 Barcelona, Spain

来源：

ANALES DE PEDIATRIA | 2011年 / 74卷 / 01期

关键词：

Meningitis; Pneumococcus; Dexamethasone; CHILDHOOD BACTERIAL-MENINGITIS; SEQUELAE; GLYCEROL; OUTCOMES; CHILDREN; FEVER;

D O I：

10.1016/j.anpedi.2010.08.013

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Our aim was two compare two different dexamethasone administration schedules in pneumococcal meningitis: short course (48 h) and long course (96 h) treatment. We diagnosed 18 pneumococcal meningitis treated with the two different schedules. We found a statistically significant longer duration of primary fever in patients who received dexamethasone for two days. We found no differences in the appearance of secondary fever, or in the development of severe neurological handicaps, or death between the two groups. We conclude that they are no significant differences between the two treatment schedules and that there is a need for developing early prognostic markers and adjuvant therapies that improve the outcome of patients with pneumococcal meningitis. (C) 2009 Asociacion Espanola de Pediatria. Published by Elsevier Espana, S.L. All rights reserved.

引用

页码：38 / 41

页数：4

共 12 条

[1] Fever interval before diagnosis, prior antibiotic treatment, and clinical outcome for young children with bacterial meningitis [J].