Mycobacterium tuberculosis Beijing genotype and risk for treatment failure and relapse, Vietnam

被引:102
作者
Lan, NTN
Lien, HTK
Tung, LB
Borgdorff, MW
Kremer, K
van Soolingen, D
机构
[1] Natl Inst Publ Hlth & Environm, NL-3720 BA Bilthoven, Netherlands
[2] Pham Ngoc Thach Tuberculosis & Lund Dis Ctr, Ho Chi Minh City, Vietnam
[3] Royal NEtherlands Tuberculosis Assoc, The Hague, Netherlands
[4] Univ Amsterdam, NL-1012 WX Amsterdam, Netherlands
关键词
D O I
10.3201/eid0912.030169
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Among 2,901 new smear-positive tuberculosis cases in Ho Chi Minh City, Vietnam, 40 cases of treatment failure and 39 relapsing cases were diagnosed. All initial and follow-up Mycobacterium tuberculosis isolates of these case-patients had (nearly) identical restriction fragment length polymorphism patterns, and the Beijing genotype was a significant risk factor for treatment failure and relapse (odds ratio 2.8, 95% confidence interval 1.5 to 5.2).
引用
收藏
页码:1633 / 1635
页数:3
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