Direct Patterning of protein- and cell-resistant polymeric monolayers and microstructures

被引:109
作者
Khademhosseini, A
Jon, S
Suh, KY
Tran, TNT
Eng, G
Yeh, J
Seong, J
Langer, R
机构
[1] MIT, Dept Biol Engn, Cambridge, MA 02142 USA
[2] MIT, Dept Chem Engn, Cambridge, MA 02142 USA
[3] Harvard Mit Div Hlth Sci & Technol, Cambridge, MA 02139 USA
关键词
SELF-ASSEMBLED MONOLAYERS; POLY(ETHYLENE GLYCOL); MAMMALIAN-CELLS; SURFACES; FABRICATION; COCULTURES; HEPATOCYTES; ATTACHMENT; SYSTEMS; FILMS;
D O I
10.1002/adma.200305433
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A novel method of patterning cells and proteins with a copolymer comprised of poly-anchoring groups is presented. As such, the technique allows for control over surface topography and surface molecules. The potential use of the technique for the development of improved biosensors and analytical tools is an area of active research.
引用
收藏
页码:1995 / 2000
页数:6
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