Pregnancy outcome in women with morbid obesity

被引:160
作者
Kumari, AS [1 ]
机构
[1] Al Mafraq Hosp, Dept Obstet & Gynecol, Abu Dhabi, U Arab Emirates
关键词
morbid obesity; pregnancy; perinatal outcome; gestational diabetes; macrosomia;
D O I
10.1016/S0020-7292(00)00391-X
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Objective: To study the effects of morbid obesity defined as a first trimester maternal body mass index of > 40 on the perinatal outcome. Methods: One hundred and eighty-eight singleton pregnancies of women with first trimester BMI > 40 who delivered at Al-Mafraq Hospital, Abu Dhabi during 1996-1998 were studied. A control group of normal body mass index matched for age and parity were selected and the perinatal variables were compared between groups. Morbidly obese women with diabetes and hypertension antedating the index pregnancy were later excluded and the data were re-analyzed. Results: Morbidly obese women were noted to have significantly adverse perinatal outcomes including hypertensive disorders of pregnancy (28.8 vs. 2.9%, P < 0.0001), gestational diabetes (24.5 vs. 2.2%, P < 0.0001), cesarian section (15.2 vs. 9.3%, P < 0.05) and macrosomia (32.6 vs. 9.3%, P < 0.001) compared to non-obese women. However, we noted a significantly lower rate of prematurity in the obese group (0.5 vs. 5.3%, P < 0.001). Even when morbidly obese women with (a) diabetes and hypertension antedating the index pregnancy and (b) those who developed gestational diabetes and/or pregnancy-induced hypertension during the index pregnancy were excluded from the analysis, significant differences in the perinatal outcomes still persisted. Conclusion: Morbid obesity appears to be an independent risk factor for adverse perinatal outcome. (C) 2001 International Federation of Gynecology and Obstetrics. All rights reserved.
引用
收藏
页码:101 / 107
页数:7
相关论文
共 16 条
[1]   Pregnancy outcome and weight gain recommendations for the morbidly obese woman [J].
Bianco, AT ;
Smilen, TW ;
Davis, Y ;
Lopez, S ;
Lapinski, R ;
Lockwood, CJ .
OBSTETRICS AND GYNECOLOGY, 1998, 91 (01) :97-102
[2]   Prepregnancy weight and the risk of adverse pregnancy outcomes [J].
Cnattingius, S ;
Bergström, R ;
Lipworth, L ;
Kramer, MS .
NEW ENGLAND JOURNAL OF MEDICINE, 1998, 338 (03) :147-152
[3]  
de Groot LCPGM, 1999, NUTR REV, V57, P62
[4]   Pregnancy complications and birth outcomes in obese and normal-weight women: Effects of gestational weight change [J].
Edwards, LE ;
Hellerstedt, WL ;
Alton, IR ;
Story, M ;
Himes, JH .
OBSTETRICS AND GYNECOLOGY, 1996, 87 (03) :389-394
[5]  
ESKENAZI B, 1991, JAMA-J AM MED ASSOC, V266, P237
[6]   MATERNAL WEIGHT AND PREGNANCY COMPLICATIONS [J].
GARBACIAK, JA ;
RICHTER, M ;
MILLER, S ;
BARTON, JJ .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1985, 152 (02) :238-245
[7]  
Garrow J. S., 1983, Nutrition Abstracts and Reviews, A, V53, P697
[8]  
Isaacs J D, 1994, J Perinatol, V14, P10
[9]  
Johnson JW, 1992, AM J OBSTET GYNECOL, V167, P370
[10]   EXCESSIVE MATERNAL WEIGHT AND PREGNANCY OUTCOME [J].
JOHNSON, JWC ;
LONGMATE, JA ;
FRENTZEN, B .
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1992, 167 (02) :353-372