Advancing Respiratory Research

被引：20

作者：

Kiley, James P. ^{[1
]}

机构：

[1] NHLBI, Div Lung Dis, NIH, Rockledge Ctr 2,US Dept HHS, Bethesda, MD 20892 USA

来源：

CHEST | 2011年 / 140卷 / 02期

关键词：

STEM-CELLS; LUNG; IDENTIFICATION; INFLAMMATION; DISEASE;

D O I：

10.1378/chest.11-0774

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

Respiratory diseases remain a major public health problem in the United States and worldwide, with increasing morbidity and mortality. Substantial progress has been made to advance understanding of the basic mechanisms of lung disease and to optimize clinical management of patients with a range of respiratory diseases. Despite this progress, our knowledge of how to predict disease prior to symptoms, improve disease definition and subclassification, and target novel and new treatments in a more personalized manner still remains inadequate. This article highlights several future opportunities and challenges related to genomics and molecular characterization of lung disease, lung injury and repair, translational lung research, the microbiome, and sleep and circadian biology as potential frontiers to advance progress in respiratory biology in health and disease. CHEST 2011; 140(2):497-501

引用

页码：497 / 501

页数：5

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