Genetic support of extended-spectrum β-lactamases

被引：93

作者：

Poirel, L. ^{[1
]}

Naas, T. ^{[1
]}

Nordmann, P. ^{[1
]}

机构：

[1] Univ Paris 11, S Paris Med Sch, Hop Bicetre, Serv Bacteriol Virol, F-94275 Le Kremlin Bicetre, France

来源：

CLINICAL MICROBIOLOGY AND INFECTION | 2008年 / 14卷

关键词：

beta-lactamases; insertion sequence; integron; review; transposon;

D O I：

10.1111/j.1469-0691.2007.01865.x

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Genes encoding extended-spectrum beta-lactamases (ESBLs) have been reported in a variety of Gram-negative species, mostly in Enterobacteriaceae, Pseudomonas aeruginosa and Acinetobacter baumannii. They are mostly either TEM or SHV derivatives, CTX-M-like enzymes-now emerging worldwide-or, less frequently, VEB, GES, and PER ESBLs. The mechanisms responsible for their acquisition are very diverse, and mostly are related to insertion sequences (ISs), transposons, class 1 integrons, and also sul1-type integrons containing the ISCR1 element. This diversity of genetic vehicles at the origin of these mobilisation/acquisition processes enhances the spread of ESBLs.

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页码：75 / 81

页数：7

相关论文

共 35 条

[1] A STANDARD NUMBERING SCHEME FOR THE CLASS-A BETA-LACTAMASES [J].

AMBLER, RP ;

COULSON, AFW ;

FRERE, JM ;

GHUYSEN, JM ;

JORIS, B ;

FORSMAN, M ;

LEVESQUE, RC ;

TIRABY, G ;

WALEY, SG .

BIOCHEMICAL JOURNAL, 1991, 276 :269-270

[2] Novel genetic structure associated with an extended-spectrum β-lactamase blaVEBGene in a Providencia stuartii clinical isolate from Algeria [J].

Aubert, D ;

Naas, T ;

Lartigue, MF ;

Nordmann, P .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2005, 49 (08) :3590-3592

[3] Functional and structural characterization of the genetic environment of an extended-spectrum β-lactamase blaVEB gene from a Pseudomonas aeruginosa isolate obtained in India [J].

Aubert, D ;

Girlich, D ;

Naas, T ;

Nagarajan, S ;

Nordmann, P .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2004, 48 (09) :3284-3290

[4] Growing group of extended-spectrum β-lactamases:: The CTX-M enzymes [J].

Bonnet, R .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2004, 48 (01) :1-14

[5] Molecular characterization of a new class 3 integron in Klebsiella pneumoniae [J].

Correia, M ;

Boavida, F ;

Grosso, F ;

Salgado, MJ ;

Lito, LM ;

Cristino, JM ;

Mendo, S ;

Duarte, A .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2003, 47 (09) :2838-2843

[6] Clinical strain of Pseudomonas aeruginosa carrying a blaTEM-21 gene located on a chromosomal interrupted TnA type transposon [J].

Dubois, V ;

Arpin, C ;

Noury, P ;

Quentin, C .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2002, 46 (11) :3624-3626

[7] Molecular characterization of a novel class 1 integron containing blaGES-1 and a fused product of aac(3)-ib/Aac(6′)-Ib′ gene cassettes in Pseudomonas aeruginosa [J].

Dubois, W ;

Poirel, L ;

Marie, C ;

Arpin, C ;

Nordmann, P ;

Quentin, C .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2002, 46 (03) :638-645

[8] Evolutionary mapping of the SHV β-lactamase and evidence for two separate IS26-dependent blaSHV mobilization events from the Klebsiella pneumoniae chromosome [J].

Ford, PJ ;

Avison, MB .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2004, 54 (01) :69-75

[9] Comparative genomics of multidrug resistance in Acinetobacter baumannii [J].

Fournier, Pierre-Edouard ;

Vallenet, David ;

Barbe, Valerie ;

Audic, Stephane ;

Ogata, Hiroyuki ;

Poirel, Laurent ;

Richet, Herve ;

Robert, Catherine ;

Mangenot, Sophie ;

Abergel, Chantal ;

Nordmann, Patrice ;

Weissenbach, Jean ;

Raoult, Didier ;

Claverie, Jean-Michel .

PLOS GENETICS, 2006, 2 (01) :62-72

[10] TLA-2, a novel ambler class a expanded-spectrum β-lactamase [J].

Girlich, D ;

Poirel, L ;

Schlüter, A ;

Nordmann, P .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2005, 49 (11) :4767-4770

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