Murine echocardiography: A practical approach for phenotyping genetically manipulated and surgically modeled mice

被引：51

作者：

Syed, F ^{[1
]}

Diwan, A ^{[1
]}

Hahn, HS ^{[1
]}

机构：

[1] Univ Cincinnati, Div Cardiol, Cincinnati, OH 45267 USA

来源：

JOURNAL OF THE AMERICAN SOCIETY OF ECHOCARDIOGRAPHY | 2005年 / 18卷 / 09期

关键词：

D O I：

10.1016/j.echo.2005.05.001

中图分类号：

R5 [内科学];

学科分类号：

1002 [临床医学]; 100201 [内科学];

摘要：

There have now been literally hundreds of genetically manipulated mouse models developed during the past decade of cardiac research. Echocardiography is considered an extremely important tool to noninvasively assess and serially follow the phenotype of genetically and surgically altered mice. This review describes in detail the technical considerations, various routinely used methods to assess cardiac function, and some emerging techniques in the assessment of cardiac function in experimental mouse models of cardiac disease.

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收藏

页码：982 / 990

页数：9

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