A potential role for the hippocampus in energy intake and body weight regulation

被引:137
作者
Davidson, Terry L. [1 ]
Kanoski, Scott E. [1 ]
Schier, Lindsey A. [1 ]
Clegg, Deborah J. [2 ]
Benoit, Stephen C. [2 ]
机构
[1] Purdue Univ, Dept Psychol Sci, Ingest Behav Res Ctr, W Lafayette, IN 47907 USA
[2] Univ Cincinnati, Dept Psychiat, Obes Res Ctr, Cincinnati, OH USA
关键词
D O I
10.1016/j.coph.2007.10.008
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Recent research and theory point to the possibility that hippocampal-dependent learning and memory mechanisms translate neurohormonal signals of energy balance into adaptive behavioral outcomes involved with the inhibition of food intake. The present paper summarizes these findings and ideas and considers the hypothesis that excessive caloric intake and obesity may be produced by dietary and other factors that are known to alter hippocampal functioning.
引用
收藏
页码:613 / 616
页数:4
相关论文
共 49 条
[1]   Insulin and leptin as adiposity signals [J].
Benoit, SC ;
Clegg, DJ ;
Seeley, RJ ;
Woods, SC .
RECENT PROGRESS IN HORMONE RESEARCH, VOL 59: CARDIOVASCULAR ENDOCRINOLOGY & OBESITY, 2004, 59 :267-285
[2]   The impact of diabetes on cognition: What can be learned from rodent models? [J].
Biessels, GJ ;
Gispen, WH .
NEUROBIOLOGY OF AGING, 2005, 26 :S36-S41
[3]   Analysis of direct hippocampal cortical field CA1 axonal projections to diencephalon in the rat [J].
Cenquizca, Lee A. ;
Swanson, Larry W. .
JOURNAL OF COMPARATIVE NEUROLOGY, 2006, 497 (01) :101-114
[4]   Little and often: Ingestive behavior patterns following hippocampal lesions in rats [J].
Clifton, PG ;
Vickers, SP ;
Somerville, EM .
BEHAVIORAL NEUROSCIENCE, 1998, 112 (03) :502-511
[5]   Gastrointestinal regulation of food intake [J].
Cummings, David E. ;
Overduin, Joost .
JOURNAL OF CLINICAL INVESTIGATION, 2007, 117 (01) :13-23
[6]   A ROLE FOR HIPPOCAMPUS IN THE UTILIZATION OF HUNGER SIGNALS [J].
DAVIDSON, TL ;
JARRARD, LE .
BEHAVIORAL AND NEURAL BIOLOGY, 1993, 59 (02) :167-171
[7]   The interoceptive cue properties of ghrelin generalize to cues produced by food deprivation [J].
Davidson, TL ;
Kanoski, SE ;
Tracy, AL ;
Walls, EK ;
Clegg, D ;
Benoit, SC .
PEPTIDES, 2005, 26 (09) :1602-1610
[8]   Memory inhibition and energy regulation [J].
Davidson, TL ;
Kanoski, SE ;
Walls, EK ;
Jarrard, LE .
PHYSIOLOGY & BEHAVIOR, 2005, 86 (05) :731-746
[9]   Persistence of abnormal neural responses to a meal in postobese individuals [J].
DelParigi, A ;
Chen, K ;
Salbe, AD ;
Hill, JO ;
Wing, RR ;
Reiman, EM ;
Tataranni, PA .
INTERNATIONAL JOURNAL OF OBESITY, 2004, 28 (03) :370-377
[10]   Effects of a fixed meal pattern on ghrelin secretion: Evidence for a learned response independent of nutrient status [J].
Drazen, DL ;
Vahl, TP ;
D'Alessio, DA ;
Seeley, RJ ;
Woods, SC .
ENDOCRINOLOGY, 2006, 147 (01) :23-30