Chromatin modification: How to put a HAT on the histones

被引：15

作者：

Travers, A ^{[1
]}

机构：

[1] MRC, Mol Biol Lab, Cambridge CB2 2QH, England

来源：

CURRENT BIOLOGY | 1999年 / 9卷 / 01期

关键词：

D O I：

10.1016/S0960-9822(99)80037-2

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Specific patterns of acetylation of the core histones are associated with specific structures and functions of chromatin. A basis for the specificity of acetylation is now apparent in the recent crystal structures of two acetyltransferases.

引用

页码：R23 / +

页数：4

共 17 条

[1] The N tails of histones H3 and H4 adopt a highly structured conformation in the nucleosome
Baneres, JL
Martin, A
Parello, J
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1997, 273 (03) : 503 - 508
[2] Structure of the histone acetyltransferase Hat1: A paradigm for the GCN5-related N-acetyltransferase superfamily
Dutnall, RN
Tafrov, ST
Sternglanz, R
Ramakrishnan, V
[J]. CELL, 1998, 94 (04) : 427 - 438
[3] Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: Characterization of an Ada complex and the SAGA (Spt/Ada) complex
Grant, PA
Duggan, L
Cote, J
Roberts, SM
Brownell, JE
Candau, R
Ohba, R
OwenHughes, T
Allis, CD
Winston, F
Berger, SL
Workman, JL
[J]. GENES & DEVELOPMENT, 1997, 11 (13) : 1640 - 1650
[4] Histone acetylation in chromatin structure and transcription
Grunstein, M
[J]. NATURE, 1997, 389 (6649) : 349 - 352
[5] Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain
Gu, W
Roeder, RG
[J]. CELL, 1997, 90 (04) : 595 - 606
[6] Acetylation of general transcription factors by histone acetyltransferases
Imhof, A
Yang, XJ
Ogryzko, VV
Nakatani, Y
Wolffe, AP
Ge, H
[J]. CURRENT BIOLOGY, 1997, 7 (09) : 689 - 692
[7] Eukaryotic transcription: An interlaced network of transcription factors and chromatin-modifying machines
Kadonaga, JT
[J]. CELL, 1998, 92 (03) : 307 - 313
[8] IDENTIFICATION OF A GENE ENCODING A YEAST HISTONE H4 ACETYLTRANSFERASE
KLEFF, S
ANDRULIS, ED
ANDERSON, CW
STERNGLANZ, R
[J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1995, 270 (42) : 24674 - 24677
[9] Crystal structure of the nucleosome core particle at 2.8 angstrom resolution
Luger, K
Mader, AW
Richmond, RK
Sargent, DF
Richmond, TJ
[J]. NATURE, 1997, 389 (6648) : 251 - 260
[10] GCN5-related histone N-acetyltransferases belong to a diverse superfamily that includes the yeast SPT10 protein
Neuwald, AF
Landsman, D
[J]. TRENDS IN BIOCHEMICAL SCIENCES, 1997, 22 (05) : 154 - 155

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