The LexA protein from Deinococcus radiodurans is not involved in RecA induction following γ irradiation

被引:89
作者
Narumi, I
Satoh, K
Kikuchi, M
Funayama, T
Yanagisawa, T
Kobayashi, Y
Watanabe, H
Yamamoto, K
机构
[1] Japan Atom Energy Res Inst, Takasaki Radiat Chem Res Estab, Biotechnol Lab, Takasaki, Gumma 3701292, Japan
[2] Tokyo Univ Agr & Technol, United Grad Sch Agr Sci, Fuchu, Tokyo 1838509, Japan
[3] Utsunomiya Univ, Fac Agr, Utsunomiya, Tochigi 3218505, Japan
[4] Tohoku Univ, Dept Biomol Sci, Grad Sch Life Sci, Sendai, Miyagi 9808578, Japan
关键词
D O I
10.1128/JB.183.23.6951-6956.2001
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
The involvement of LexA in induction of RecA was investigated in Deinococcus radiodurans. As in the wild-type strain, an increase in RecA protein synthesis following gamma irradiation was detected in a lexA disruptant, indicating that LexA is not involved in the induction of RecA in D. radiodurans.
引用
收藏
页码:6951 / 6956
页数:6
相关论文
共 43 条
[1]  
[Anonymous], 1983, PHOTOCHEM PHOTOBIOL
[2]   Conserved domains in DNA repair proteins and evolution of repair systems [J].
Aravind, L ;
Walker, DR ;
Koonin, EV .
NUCLEIC ACIDS RESEARCH, 1999, 27 (05) :1223-1242
[3]  
Battista Jr, 1998, CONT CANC RES, P287
[4]   Against all odds: The survival strategies of Deinococcus radiodurans [J].
Battista, JR .
ANNUAL REVIEW OF MICROBIOLOGY, 1997, 51 :203-224
[5]   Expression of recA in Deinococcus radiodurans [J].
Carroll, JD ;
Daly, MJ ;
Minton, KW .
JOURNAL OF BACTERIOLOGY, 1996, 178 (01) :130-135
[6]   REPAIR OF X-RAY DAMAGE TO DEOXYRIBONUCLEIC ACID IN MICROCOCCUS RADIODURANS [J].
DEAN, CJ ;
FELDSCHR.P ;
LETT, JT .
NATURE, 1966, 209 (5018) :49-&
[7]   A phylogenomic study of DNA repair genes, proteins, and processes [J].
Eisen, JA ;
Hanawalt, PC .
MUTATION RESEARCH-DNA REPAIR, 1999, 435 (03) :171-213
[8]   SOLUTION STRUCTURE OF THE LEXA REPRESSOR DNA-BINDING DOMAIN DETERMINED BY H-1-NMR SPECTROSCOPY [J].
FOGH, RH ;
OTTLEBEN, G ;
RUTERJANS, H ;
SCHNARR, M ;
BOELENS, R ;
KAPTEIN, R .
EMBO JOURNAL, 1994, 13 (17) :3936-3944
[9]  
FRIEDBERG EC, 1995, DNA REPAIR MUTAGENES
[10]   Identification and disruption analysis of the recN gene in the extremely radioresistant bacterium Deinococcus radiodurans [J].
Funayama, T ;
Narumi, I ;
Kikuchi, M ;
Kitayama, S ;
Watanabe, H ;
Yamamoto, K .
MUTATION RESEARCH-DNA REPAIR, 1999, 435 (02) :151-161