Parkinson's disease and environmental factors - Matched case-control study in the Limousin region, France

被引：63

作者：

Preux, PM

Condet, A

Anglade, C

Druet-Cabanac, M

Debrock, C

Macharia, W

Couratier, P

Boutros-Toni, F

Dumas, M

机构：

[1] Fac Med Limoges, Inst Neurol Epidemiol & Trop Neurol, F-87025 Limoges, France

[2] Fac Med Limoges, Dept Biostat & Med Informat, F-87025 Limoges, France

[3] Dupuytren Univ Hosp, Dept Neurol, Limoges, France

来源：

NEUROEPIDEMIOLOGY | 2000年 / 19卷 / 06期

关键词：

Parkinson's disease; environment; matched case-control study; Limousin region; logistic regression;

D O I：

10.1159/000026273

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The study included 140 patients with Parkinson's disease (PD) and 280 non-Parkinson age-matched controls to evaluate environmental risk factors associated with PD. The effect of exposure to environmental and dietary factors was determined using conditional logistic regression. This multivariate analysis showed that PD in first-degree relatives and tea drinking were the main risk factors for PD, Smoking appeared to be a protective factor. Exposure to toxic compounds was not a significant risk factor. Further research is needed to validate that tea consumption increases the risk of PD. Copyright (C) 2000 S. Karger AG, Basel.

引用

页码：333 / 337

页数：5

共 12 条

[1] FAMILIAL PARKINSONS-DISEASE - A CLINICAL GENETIC-ANALYSIS [J].