Understanding functional diversity and substrate specificity in haem peroxidases: what can we learn from ascorbate peroxidase?

被引:63
作者
Raven, EL [1 ]
机构
[1] Univ Leicester, Dept Chem, Leicester LE1 7RH, Leics, England
关键词
D O I
10.1039/b210426c
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This review summarizes the most recent advances in our understanding of the haern enzyme ascorbate peroxidase. The aim is to show how the combined applications of protein engineering, mechanistic and structural studies can be used to provide an overall picture of enzyme catalysis, and how this information can be used to provide new insight into other, more well-characterized peroxidases (in particular cytochrome c peroxidase). It contains 212 references and covers literature up to March 2003.
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页码:367 / 381
页数:15
相关论文
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