Lymphocyte signalling: A coordinating role for Vav?

被引：67

作者：

Cantrell, D ^{[1
]}

机构：

[1] Imperial Canc Res Fund, Lymphocyte Activat Lab, London WC2A 3PX, England

来源：

CURRENT BIOLOGY | 1998年 / 8卷 / 15期

关键词：

D O I：

10.1016/S0960-9822(07)00341-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Vav1 is a guanine nucleotide exchange factor that selectively activates the Rad GTPase and is expressed specifically in haematopoietic cells. Recent work has revealed how Vav1 integrates signals from lymphocyte antigen receptors and costimulatory receptors to control immune function.

引用

页码：R535 / R538

页数：4

共 15 条

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