Targeting FGF receptors in colorectal cancer: from bench side to bed side

被引：9

作者：

Abdel-Rahman, Omar ^{[1
]}

机构：

[1] Ain Shams Univ, Fac Med, Dept Clin Oncol, Cairo, Egypt

来源：

FUTURE ONCOLOGY | 2015年 / 11卷 / 09期

关键词：

brivanib; FGFR; gastrointestinal cancer; regorafenib; GROWTH-FACTOR RECEPTORS; DRUG-RESISTANCE; FIBROBLAST; REGORAFENIB; INHIBITOR; MULTICENTER; THERAPY; PLACEBO;

D O I：

10.2217/fon.15.38

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Successful management of advanced colorectal cancer has been a challenging job for practicing oncologists as well as a priority for the oncology research community. The better understanding of the underlying patho-biology and critical pathway targets in this disease has contributed to major developments in that direction. In this review, we will revise the different biological and clinical aspects related to the use of FGFR pathway-targeted therapies in advanced colorectal cancer with particular focus on future perspectives in that regard.

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收藏

页码：1373 / 1379

页数：7

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