Nucleocytoplasmic transport: Driving and directing transport

被引:86
作者
Cole, CN [1 ]
Hammell, CM [1 ]
机构
[1] Dartmouth Coll, Sch Med, Dept Biochem, Hanover, NH 03755 USA
关键词
D O I
10.1016/S0960-9822(98)70239-8
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Nucleocytoplasmic transport involves assembly and movement across the nuclear envelope of cargo-receptor complexes that interact with the small GTPase Ran. The asymmetric distribution of Ran regulator proteins, RanGAP1 and RCC1, provides the driving force and directionality for nuclear transport. (C) Current Biology Ltd ISSN 0960-9822.
引用
收藏
页码:R368 / R372
页数:5
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