JC virus as a marker of human migration to the Americas

被引:60
作者
Stoner, GL
Jobes, DV
Cobo, MF
Agostini, HT
Chima, SC
Ryschkewisch, CF
机构
[1] NINDS, Neurotoxicol Sect, NIH, Bethesda, MD 20892 USA
[2] ANLIS INEI, Dept Virus, Serv Biol Mol, RA-1281 Buenos Aires, DF, Argentina
[3] Univ Freiburg, Dept Ophthalmol, D-79106 Freiburg, Germany
关键词
JC virus; polyomavirus; Native Americans; African Americans; Hispanic Americans; phylogeny;
D O I
10.1016/S1286-4579(00)01339-3
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
JC virus is a ubiquitous human polyomavirus present in populations worldwide. Seven genotypes differing in DNA sequence by similar to1-3% characterize three Old World population groups (African, European and Asian) as well as Oceania. It is possible to follow Old World populations into the New World by the JC virus genotypes they carried. The first population to settle in the Americas, the Native Americans, brought with them type 2A from northeast Asia. European settlers arriving after Columbus carried primarily type 1 and type 4. Africans brought by the slave trade carried type 3 and type 6. (C) 2000 Editions scientifiques er medicales Elsevier SAS.
引用
收藏
页码:1905 / 1911
页数:7
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