The apicoplast:: a new member of the plastid family

被引:74
作者
Maréchal, E
Cesbron-Delauw, MF
机构
[1] Univ Grenoble 1, CEA, Physiol Cellulaire Vegetale Lab, CNRS,UMR 5019, F-38054 Grenoble 9, France
[2] Univ Grenoble 1, Lab Pathogenese Sporozoaires, EP 2029 CNRS, F-38041 Grenoble, France
关键词
D O I
10.1016/S1360-1385(01)01921-5
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Protozoan parasites of the phylum Apicomplexa include pathogens such as Plasmodium, Toxoplasma and Cryptosporidium. They have been shown to contain a vestigial nonphotosynthetic plastid, the apicoplast. which might have arisen by secondary endosymbiosis. Little is known about the function of the apicoplast but the parasites exhibit delayed cell death when their apicoplast is impaired. The discovery of the apicoplast opens an unexpected opportunity to link current fundamental research on plant and algal plastids to the physiology of apicomplexans. For example, the apicoplast might provide new targets for innovative drugs that act as herbicides end do not affect the mammalian host.
引用
收藏
页码:200 / 205
页数:6
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