(Neuro)inflammation and neuroprogression as new pathways and drug targets in depression: From antioxidants to kinase inhibitors

被引:106
作者
Maes, Michael [3 ]
Leonard, Brian [1 ]
Fernandez, Alberto [2 ]
Kubera, Marta [4 ]
Nowak, Gabriel [5 ]
Veerhuis, Rob [6 ]
Gardner, Ann [7 ]
Ruckoanich, Piaynuj [3 ]
Geffard, Michel [8 ]
Altamura, Carlo [9 ]
Galecki, Piotr [10 ]
Berk, Michael [11 ,12 ]
机构
[1] Natl Univ Ireland, Dept Pharmacol, Galway, Ireland
[2] Palau Pharma, Barcelona, Spain
[3] Piyavate Hosp, Bangkok, Thailand
[4] Polish Acad Sci, Inst Pharmacol, Dept Expt Endocrinol, Krakow, Poland
[5] Polish Acad Sci, Inst Pharmacol, Dept Neurobiol, Krakow, Poland
[6] Vrije Univ Amsterdam, Med Ctr, Amsterdam, Netherlands
[7] Karolinska Inst, Div Psychiat, Stockholm, Sweden
[8] Assoc Inst Res & Dev Human Pathol & Therapy, Bordeaux, France
[9] Univ Milan, Dept Psychiat, I-20122 Milan, Italy
[10] Med Univ Lodz, Dept Adult Psychiat, Lodz, Poland
[11] Univ Melbourne, Dept Clin & Biomed Sci, Melbourne, Vic 3010, Australia
[12] Univ Melbourne, Orygen Res Ctr, Ctr Youth Mental Hlth, Melbourne, Vic 3010, Australia
关键词
JAK-STAT PATHWAY; ACTIVATED PROTEIN-KINASE; PLACEBO-CONTROLLED TRIAL; NECROSIS-FACTOR-ALPHA; FORCED-SWIM TEST; NF-KAPPA-B; MAJOR DEPRESSION; INTERFERON-GAMMA; DOUBLE-BLIND; HIPPOCAMPAL NEUROGENESIS;
D O I
10.1016/j.pnpbp.2011.02.019
中图分类号
R74 [神经病学与精神病学];
学科分类号
100204 [神经病学];
摘要
引用
收藏
页码:659 / 663
页数:5
相关论文
共 87 条
[1]
A road map for those who don't know JAK-STAT [J].
Aaronson, DS ;
Horvath, CM .
SCIENCE, 2002, 296 (5573) :1653-1655
[2]
[Anonymous], 2004, COCHRANE DB SYST REV
[3]
Neuronal cell death induced by antidepressants:: lack of correlation with Egr-1, NF-κB and extracellular signal-regulated protein kinase activation [J].
Bartholomä, P ;
Erlandsson, N ;
Kaufmann, K ;
Rössler, OG ;
Baumann, B ;
Wirth, T ;
Giehl, KM ;
Thiel, G .
BIOCHEMICAL PHARMACOLOGY, 2002, 63 (08) :1507-1516
[4]
Pathways underlying neuroprogression in bipolar disorder: Focus on inflammation, oxidative stress and neurotrophic factors [J].
Berk, M. ;
Kapczinski, F. ;
Andreazza, A. C. ;
Dean, O. M. ;
Giorlando, F. ;
Maes, M. ;
Yuecel, M. ;
Gama, C. S. ;
Dodd, S. ;
Dean, B. ;
Magalhaes, P. V. S. ;
Amminger, P. ;
McGorry, P. ;
Malhi, G. S. .
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, 2011, 35 (03) :804-817
[5]
N-acetyl cysteine for depressive symptoms in bipolar disorder - A double-blind randomized placebo-controlled trial [J].
Berk, Michael ;
Copolov, David L. ;
Dean, Olivia ;
Lu, Kristy ;
Jeavons, Sue ;
Schapkaitz, Ian ;
Anderson-Hunt, Murray ;
Bush, Ashley I. .
BIOLOGICAL PSYCHIATRY, 2008, 64 (06) :468-475
[6]
Intestinal permeability in the pathogenesis of NSAID-induced enteropathy [J].
Bjarnason, Ingvar ;
Takeuchi, Ken .
JOURNAL OF GASTROENTEROLOGY, 2009, 44 :23-29
[7]
The p38α mitogen-activated protein kinase as a central nervous system drug discovery target [J].
Borders, Aaron S. ;
de Almeida, Lucia ;
Van Eldik, Linda J. ;
Watterson, Martin .
BMC NEUROSCIENCE, 2008, 9 (Suppl 2)
[8]
The NF-κB regulatory network [J].
Brasier, Allan R. .
CARDIOVASCULAR TOXICOLOGY, 2006, 6 (02) :111-130
[9]
Acetylsalicylic acid accelerates the antidepressant effect of fluoxetine in the chronic escape deficit model of depression [J].
Brunello, Nicoletta ;
Alboni, Silvia ;
Capone, Giacomo ;
Benatti, Cristina ;
Blom, Joan M. C. ;
Tascedda, Fabio ;
Kriwin, Philippe ;
Mendlewicz, Julien .
INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY, 2006, 21 (04) :219-225
[10]
Xanthones from Mangosteen Inhibit Inflammation in Human Macrophages and in Human Adipocytes Exposed to Macrophage-Conditioned Media [J].
Bumrungpert, Akkarach ;
Kalpravidh, Ruchaneekorn W. ;
Chuang, Chia-Chi ;
Overman, Angel ;
Martinez, Kristina ;
Kennedy, Arion ;
McIntosh, Michael .
JOURNAL OF NUTRITION, 2010, 140 (04) :842-847