Changes in gut hormones after bariatric surgery

被引：67

作者：

Vincent, R. P. ^{[2
]}

le Roux, C. W. ^{[1
,2
]}

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Hammersmith Hosp, Dept Metab Med, London W12 0NN, England

[2] Kings Coll Hosp London, Dept Chem Pathol, London, England

来源：

CLINICAL ENDOCRINOLOGY | 2008年 / 69卷 / 02期

关键词：

D O I：

10.1111/j.1365-2265.2007.03164.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Bariatric surgery is one of the most effective treatments for achieving long-term weight loss in morbidly obese patients. Bariatric surgery causes weight loss through substantial decline of hunger and increased satiety. Recently our understanding of neuroendocrine regulation of food intake and weight gain, especially regarding the role of gut hormones, has significantly increased. The changes in these hormones following bariatric surgery can partly explain the mechanism behind weight loss achieved through these procedures. In this paper, we review the effect bariatric procedures have on different gut hormone levels and how they in turn can alter the complex neuroendocrine regulation of energy homeostasis.

引用

页码：173 / 179

页数：7

共 70 条

[1] Plasma ghrelin concentratin in the short-term following biliopancreatic diversion [J].

Adami, GF ;

Cordera, R ;

Marinari, G ;

Lamerini, G ;

Andraghetti, G ;

Scopinaro, N .

OBESITY SURGERY, 2003, 13 (06) :889-892

[2] HUMAN DISTRIBUTION AND RELEASE OF A PUTATIVE NEW GUT HORMONE, PEPTIDE-YY [J].

ADRIAN, TE ;

FERRI, GL ;

BACARESEHAMILTON, AJ ;

FUESSL, HS ;

POLAK, JM ;

BLOOM, SR .

GASTROENTEROLOGY, 1985, 89 (05) :1070-1077

[3] Antagonism of ghrelin receptor reduces food intake and body weight gain in mice [J].

Asakawa, A ;

Inui, A ;

Kaga, T ;

Katsuura, G ;

Fujimiya, M ;

Fujino, MA ;

Kasuga, M .

GUT, 2003, 52 (07) :947-952

[4]

AYLWIN S, 2005, CURR OPIN ENDOCRINOL, V12, P89

[5] Biology of incretins: GLP-1 and GIP [J].

Baggio, Laurie L. ;

Drucker, Daniel J. .

GASTROENTEROLOGY, 2007, 132 (06) :2131-2157

[6] Peptide YY secretion in morbidly obese patients before and after vertical banded gastroplasty [J].

Bartolomé, MA ;

Borque, M ;

Martinez-Sarmiento, J ;

Aparicio, E ;

Hernández, C ;

Cabrerizo, L ;

Fernández-Represa, JA .

OBESITY SURGERY, 2002, 12 (03) :324-327

[7] Gut hormone PYY3-36 physiologically inhibits food intake [J].

Batterham, RL ;

Cowley, MA ;

Small, CJ ;

Herzog, H ;

Cohen, MA ;

Dakin, CL ;

Wren, AM ;

Brynes, AE ;

Low, MJ ;

Ghatei, MA ;

Cone, RD ;

Bloom, SR .

NATURE, 2002, 418 (6898) :650-654

[8] Pancreatic polypeptide reduces appetite and food intake in humans [J].

Batterham, RL ;

Le Roux, CW ;

Cohen, MA ;

Park, AJ ;

Ellis, SM ;

Patterson, M ;

Frost, GS ;

Ghatei, MA ;

Bloom, SR .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2003, 88 (08) :3989-3992

[9] HAMSTER PREPROGLUCAGON CONTAINS THE SEQUENCE OF GLUCAGON AND 2 RELATED PEPTIDES [J].

BELL, GI ;

SANTERRE, RF ;

MULLENBACH, GT .

NATURE, 1983, 302 (5910) :716-718

[10] Progressive rise in gut hormone levels after Roux-en-Y gastric bypass suggests gut adaptation and explains altered satiety [J].

Borg, CM ;

le Roux, CW ;

Ghatei, MA ;

Bloom, SR ;

Patel, AG ;

Aylwin, SJB .

BRITISH JOURNAL OF SURGERY, 2006, 93 (02) :210-215

← 1 2 3 4 5 6 7 →