A blueprint for a human epigenome project: the AACR human epigenome workshop

被引:109
作者
Jones, PA
Martienssen, R
机构
[1] Univ So Calif, Norris Comprehens Canc Ctr, Los Angeles, CA 90089 USA
[2] Cold Spring Harbor Lab, Cold Spring Harbor, NY 11724 USA
关键词
D O I
10.1158/0008-5472.CAN-05-3865
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Epigenetic processes control the packaging anti function of the human genome and contribute to normal and pathologic states, including cancer. The time is ripe to undertake an international effort to identify all the chemical changes and relationships between chromatin constituents that provide function to the genetic code. A timely workshop of leading experts, convened by the American Association for Cancer Research (AACR), confirmed that the technology is at hand to begin defining human epigenomes at high resolution.
引用
收藏
页码:11241 / 11246
页数:6
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