Waldenstrom's macroglobulinemia and large B-cell central nervous system lymphoma: a case report

被引：2

作者：

Langevin, Jean-Philippe ^{[1
]}

Bergsneider, Marvin ^{[1
]}

Yashar, Parham ^{[2
]}

Makary, Raafat F. ^{[3
]}

机构：

[1] Univ Calif Los Angeles, David Geffen Sch Med, Div Neurosurg, Los Angeles, CA 90095 USA

[2] Univ So Calif, Dept Neurosurg, Los Angeles, CA 90033 USA

[3] Univ Florida, Coll Med Jacksoncille, Dept Pathol & Lab Med, Jacksonville, FL 32209 USA

来源：

SURGICAL NEUROLOGY | 2008年 / 69卷 / 04期

关键词：

lymphoma; Waldenstrom's macroglobulinemia; brain biopsy; methotrexate;

D O I：

10.1016/j.surneu.2007.05.053

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Background: Waldenstrom's macroglobulinemia is a low-grade B-cell lymphoma characterized by monoclonal synthesis and secretion of IgM antibodies [3]. The classic symptoms of WM result from blood hyperviscosity. Neurologic symptoms, such as fatigue, dizziness, and blurred vision, are common. The metastatic spread to the CNS, which rarely has been reported, can occur either diffusely or in the form of a mass lesion. Case Description: We present the case of a 73-year-old woman with intracerebral large B-cell lymphoma and concurrent WM. Conclusion: This case illustrates the importance of histopathologic diagnosis by brain biopsy despite an existing diagnosis of systemic neoplasm. (C) 2008 Elsevier Inc. All rights reserved.

引用

页码：407 / 410

页数：4

共 5 条

[1]

Bing J, 1936, ACTA MED SCAND, V88, P492

[2]

Civit T, 1997, NEUROCHIRURGIE, V43, P245

[3] Radiation therapy and combination of cladribine, cyclophosphamide, and prednisone as treatment of Bing-Neel syndrome: Case report and review of the literature [J].

Delgado, J ;

Canales, MA ;

Garcia, B ;

Alvarez-Ferreira, J ;

Garcia-Grande, A ;

Hernandez-Navarro, F ;

Andez-, H .

AMERICAN JOURNAL OF HEMATOLOGY, 2002, 69 (02) :127-131

[4]

Johnson Stephen A, 2002, Rev Clin Exp Hematol, V6, P421

[5]

Waldenstrom J, 1944, ACTA MED SCAND, V117, P216

← 1 →