Brain networks of visuospatial attention and their disruption in visual neglect

被引:156
作者
Bartolomeo, Paolo [1 ,2 ,3 ]
Thiebaut de Schotten, Michel [1 ,4 ]
Chica, Ana B. [1 ,5 ]
机构
[1] Grp Hosp Pitie Salpetriere, Brain & Spine Inst, INSERM, UPMC UMRS 975, F-75634 Paris, France
[2] Grp Hosp Pitie Salpetriere, AP HP, F-75634 Paris, France
[3] Catholic Univ, Dept Psychol, Milan, Italy
[4] Kings Coll London, Inst Psychiat, Dept Forens & Neurodev Sci, Natbrainlab, London WC2R 2LS, England
[5] Univ Granada, Dept Expt Psychol, Granada, Spain
关键词
attention; neglect; consciousness; parietal lobe; frontal lobe; STIMULUS-DRIVEN ATTENTION; LEFT UNILATERAL NEGLECT; REPRESENTATIONAL NEGLECT; SPATIAL NEGLECT; RIGHT-HEMISPHERE; LINE BISECTION; MENTAL-IMAGERY; PARIETAL LOBE; HEMISPATIAL NEGLECT; EGOCENTRIC NEGLECT;
D O I
10.3389/fnhum.2012.00110
中图分类号
Q189 [神经科学];
学科分类号
071006 [神经生物学];
摘要
Visual neglect is a multi-component syndrome including prominent attentional disorders. Research on the functional mechanisms of neglect is now moving from the description of dissociations in patients' performance to the identification of the possible component deficits and of their interaction with compensatory strategies. In recent years, the dissection of attentional deficits in neglect has progressed in parallel with increasing comprehension of the anatomy and function of large-scale brain networks implicated in attentional processes. This review focuses on the anatomy and putative functions of attentional circuits in the brain, mainly subserved by fronto-parietal networks, with a peculiar although not yet completely elucidated role for the right hemisphere. Recent results are discussed concerning the influence of a non-spatial attentional function, phasic alertness, on conscious perception in normal participants and on conflict resolution in neglect patients. The rapid rate of expansion of our knowledge of these systems raises hopes for the development of effective strategies to improve the functioning of the attentional networks in brain-damaged patients.
引用
收藏
页数:10
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