Low frequency of treatment of osteoporosis among postmenopausal women following a fracture

被引:204
作者
Andrade, SE
Majumdar, SR
Chan, KA
Buist, DSM
Go, AS
Goodman, M
Smith, DH
Platt, R
Gurwitz, JH
机构
[1] Meyers Primary Care Inst, Fallon Hlth Care Syst, Worcester, MA 01605 USA
[2] Univ Massachusetts, Worcester, MA 01605 USA
[3] Univ Alberta, Dept Med, Edmonton, AB, Canada
[4] Harvard Univ, Sch Med, Dept Ambulatory Care & Prevent, Boston, MA USA
[5] Brigham & Womens Hosp, Channing Lab, Boston, MA 02115 USA
[6] Harvard Univ, Sch Publ Hlth, Dept Epidemiol, Boston, MA USA
[7] Harvard Pilgrim Hlth Care, Boston, MA USA
[8] Grp Hlth Cooperat Puget Sound, Ctr Hlth Studies, Seattle, WA USA
[9] Kaiser Permanente No Calif, Div Res, Oakland, CA USA
[10] HealthPartners Res Fdn, Minneapolis, MN USA
[11] Kaiser Permanente NW, Portland, OR USA
关键词
D O I
10.1001/archinte.163.17.2052
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background: Osteoporosis is a major cause of morbidity. Treatment of osteopprosis reduces the risk of fracture, particularly for postmenopausal women with a history of fracture. Methods: A retrospective study was conducted using the automated databases of 7 health maintenance organizations to evaluate the use of drugs recommended for secondary prevention of osteoporotic fracture. Women 60 years and older with an inpatient or outpatient diagnostic code for a fracture of the hip, vertebra, or wrist between October 1, 1994, and September 30, 1996, and at least 1 year of continuous enrollment with a drug benefit plan following the date of fracture, were identified. The frequency of use of medications for the treatment of osteoporosis (estrogen replacement therapy, bisphosphonates, and calcitonin) during the I-year period following the date of the initial fracture was estimated overall and according to patient age, fracture site, and year of fracture. Results: During the study period, 3492 women 60 years and older were diagnosed with a fracture of the hip, vertebra, or wrist, and met the inclusion criteria. Of these patients, 822 (24%) received a drug for osteoporosis treatment during the year following the fracture. The proportion of women receiving treatment for osteoporosis was approximately 2-fold higher among those with a fracture of the vertebra (44%) than among those with a fracture of the hip (21%) or wrist (23%) (P < .001). Of the 2605 women who had not been treated for osteoporosis in the 90 days before a fracture, 14% received treatment for osteoporosis in the year following a fracture. Increasing age was associated with a reduced likelihood of receiving osteoporosis treatment (P < .001). Conclusions: Most of the older women who had experienced a fracture of the hip, vertebra, or wrist did not receive drug treatment for osteoporosis within 1 year following the fracture. Interventions to improve the detection and treatment of osteoporosis in high-risk patients need to be developed.
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收藏
页码:2052 / 2057
页数:6
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